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Pitching A No-Hitter

Biotech Letter

Today, let’s look into a player in the biotechnology and healthcare sector that’s not just aiming to hit it big; they’re looking to knock it out of the park.

Now, what makes a stock a true all-star in beating the market? I’d bet my last dollar it’s the potential for some serious earnings growth.

And guess who’s up to bat with that? I’m pointing at Vertex Pharmaceuticals (VRTX), and let me tell you, they’re not playing small ball. They’re looking at 2024 like it’s their championship game, ready to trounce the market.

As we all know, these guys are sitting on a goldmine with their cystic fibrosis (CF) drugs, where they have a virtual monopoly of the space. They’ve been working like mad scientists to expand their labels and get more reimbursement deals. It’s like they’re on a mission to cover every base.

Take Trikafta, for instance. This drug is a game-changer, making life better for folks with CF. We’re talking about a treatment that’s in a league of its own, catering to 90% of those battling CF because of its effectiveness.

In 2023 alone, Vertex’s CFTR modulators, with Trikafta leading the pack, pulled in a cool $9.8 billion. That’s an 11% jump from the previous year.

But hold your applause, because Vertex’s isn’t done yet. The biotech introduced a new product, the “vanza triple.”

This up-and-coming contender’s stepping up to the plate, showing it can go toe-to-toe with Trikafta, improving lung function and even outperforming the blockbuster drug in reducing sweat chloride levels.

And it’s a once-daily pill, which is like hitting a home run for patients who are tired of the twice-daily routine.

Vertex is swinging for the fences, aiming to get regulatory approval for this new heavy hitter by mid-year. And if the trials are any indication, we’re looking at another blockbuster in the making.

Now, let’s talk numbers, because that’s what really scores the runs.

Vertex wrapped up 2023 with product revenue hitting $9.9 billion, up 11% from the year before.

Trikafta/Kaftrio was the MVP, bringing in $8.9 billion. Looking ahead, Vertex is projecting revenues between $10.55 billion and $10.75 billion for this year.

But it’s not all about CF with these guys. They’re looking to diversify, stepping into the batter’s box with treatments outside of CF.

A prime example is their ongoing collaboration with CRISPR Therapeutics (CRSP) on Casgevy, a gene therapy that’s just cleared the bases with FDA approval for sickle cell disease and transfusion-dependent beta-thalassemia.

And let’s not forget VX-548, their non-opioid pain relief drug that’s rounding third base and heading for home with promising trial results.

So, what’s the game plan for those who want to get in on the action?

Well, Vertex’s PEG ratio is sitting pretty at 0.58, signaling that this team is undervalued given the growth potential they’re packing. Sure, their valuation might look high with a P/E ratio north of the healthcare average, but with a lineup like theirs, it’s a premium worth paying.

That means if you’re willing to play the long game and not just looking for a quick win, Vertex is a team you might want to draft for your portfolio. They’ve got a solid lineup, from their CF franchise to gene therapy breakthroughs and beyond.

And with their sights set on more than just the next 12 months, those analyst price targets might just be the floor for where this team can go.

In the big league of biotech and healthcare, Vertex is proving that it has what it takes to be a powerhouse. With innovation at the bat and a strategy that covers all bases, they’re a team worth watching — and maybe even cheering for.

 

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