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Tag Archive for: (SNY)

Mad Hedge Fund Trader

Getting You Bang per Buck with Alexion Pharmaceuticals

Biotech Letter

Since nobody can actually control when to get sick or what type of disease to acquire, it makes absolute sense that biotech stocks remain one of the wisest bets if you want to put your hard-earned cash to work.

The question, therefore, is what are the best biotech stocks to buy now?

Looking at the biotechnology stock prices today, I can say that Alexion Pharmaceuticals (ALXN) will give you the most bang for your buck.

For over a decade, this ultra-rare-disease biotechnology company had been regularly valued at roughly 22 to 67 times its cash flow and frequently well above 30 times forward EPS.

Now, you can buy this top biotech stock for less than eight times its Wall Street profit consensus in 2021 and 10 times its cash flow for next year as well. It definitely doesn’t hurt that its PEG ratio is less than 1, categorizing it as an “undervalued” stock today.

However, its attractive pricing isn’t the only thing that’s putting Alexion in the news these days as this biotech company has been active in the race to find a coronavirus cure since early February.

When news about the pandemic broke, Alexion decided to repurpose its rare chronic blood disease bestseller Soliris as a potential COVID-19 treatment since the drug showed promising results on patients with severe pneumonia or acute respiratory distress syndrome.

Alexion’s efforts have been quite promising so far, with the biotech company targeting to commence a Phase 2 study of Soliris within the month. What we know so far is that this experiment will involve 10 patients as part of the proof-of-concept trial.

Apart from Alexion, other top biotech companies repurposing old drugs in search of a COVID-19 cure are Gilead Sciences (GILD) with Remdesivir, Roche (RHHBY) with Actemra, and Regeneron (REGN) and Sanofi (SNY) with Kevzara.

Outside its coronavirus treatment efforts, Alexion actually prides itself on a promising pipeline. To date, three treatments are projected to turn into blockbusters soon.

The first is Strensiq, which is formulated to treat a rare disease commonly known as hypophosphatasia. Patients with this disorder have an enzyme deficiency, making them unable to properly process calcium and phosphorus. As a result, they end up with malformed bones and teeth.

The second treatment is Kanuma, which is for patients suffering from lysosomal acid lipase (LAP) deficiency. People with this condition lack a key enzyme, preventing them from effectively breaking down fats.

Both conditions are extremely rare. Hypophosphatasia affects only 1 in 100,000 people while LAP is suffered by 1 in 40,000 individuals.

The third treatment is Ultomiris, which is widely regarded as Soliris’ successor.

For years, Soliris has been Alexion’s major moneymaker. However, uncertainties on the company’s hold on its patent exclusivity have started to shake investors’ faith in this stock. With one of Soliris’ key patents set to expire in 2021, the biotech company has to brace itself for the onslaught of generic competition.

This is where Ultomiris comes in.

Alexion has been busy migrating its customers to opt for Ultomiris before Soliris’ key patent expires.

To make this offer enticing, the biotech company has priced the newer drug to be slightly cheaper than the old blockbuster. Ultomiris costs $458,000 while Soliris is priced at $500,000.

To sweeten the deal further, the newer treatment is only required once every eight weeks. In comparison, Soliris’ treatment schedule is bi-monthly.

Basically, it’s as if Alexion has effectively restarted the clock in its patent exclusivity on this ultra-rare disease indication. The company aims to convert at least 70% of its users by mid-2020.

From a financial point of view, Alexion is performing quite well. Its fourth-quarter report showed that the company earned $1.4 billion in revenues, demonstrating a 23% increase from the same quarter in 2018.

Meanwhile, it raked in $5 billion in full-year sales for 2019. This indicated a 21% jump from its relatively paltry sales of $4.1 billion.

Looking at the metrics, Alexion is one of the surprisingly cheap stocks considering its growth. It also has the added bonus of dominating its chosen ultra-rare disease space.

This is typically a good strategy to avoid competition while also being able to seek high price points for its innovative treatments. The fact that insurers generally cover these treatments all but guarantees that Alexion is secure in terms of cash flow predictability.

Despite the panic induced by the coronavirus market, investing opportunities are everywhere --- if you know where to look.

Alexion is a solid company with strong growth prospects and is selling at a reasonable price. Any opportunistic investor worth his salt would know that this is the ideal time to strike.

 

https://www.madhedgefundtrader.com/wp-content/uploads/2020/04/alxn.png 111 255 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-04-21 04:00:032020-04-20 21:01:23Getting You Bang per Buck with Alexion Pharmaceuticals
Mad Hedge Fund Trader

March 31, 2020

Diary, Newsletter, Summary

Global Market Comments
March 31, 2020
Fiat Lux

Featured Trade:

(MORE PLAYERS ENTER THE RACE FOR A CORONA CURE)
 (MRNA), (ARCT), (JNJ), (SNY),  (GOVX), (ALT), (NVAX), (GSK), (GNBT), (VXL.V), (INO), (APDN), (CADILAHC)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-31 07:04:572020-03-31 06:55:37March 31, 2020
Mad Hedge Fund Trader

March 31, 2020

Biotech Letter

Mad Hedge Biotech & Healthcare Letter
March 31, 2020
Fiat Lux

Featured Trade:

(MORE PLAYERS ENTER THE RACE FOR A CORONA CURE)
 (MRNA), (ARCT), (JNJ), (SNY),  (GOVX), (ALT), (NVAX), (GSK), (GNBT), (VXL.V), (INO), (APDN), (CADILAHC)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-31 07:04:492020-03-31 07:31:53March 31, 2020
Mad Hedge Fund Trader

More Players Enter the Race for a Corona Cure

Biotech Letter, Diary, Newsletter

Special issue on COVID-19 vaccines: Moderna Inc (MRNA), Arcturus (ARCT), Johnson & Johnson (JNJ), Sanofi (SNY), GeoVax (GOVX), Altimmune (ALT), Novavax (NVAX), GlaxoSmithKline (GSK), Generex (GNBT), Vaxil Bio (VXL.V), Inovio Pharmaceuticals (INO), Applied DNA Sciences (APDN), Zydus Cadila (CADILAHC)

The hunt is definitely underway for potential treatments to fight COVID-19 but coming up with vaccines will take a much longer time.

Since we already have the genetic code of the novel coronavirus (click here for the link), researchers can now use the complete blueprint to come up with ways to defeat this disease.

With code in hand, it takes a supercomputer just three hours to create model vaccines. Then it is just a question of how fast you can make them, if at all. Many proposed models are far beyond our existing technology.

To date, there are roughly 35 companies and academic organizations actively seeking ways to come up with a COVID-19 vaccine. While the process will still take time, there are several promising prospects.

Among the companies working on this, Moderna Inc (MRNA) has been recognized as the first biotechnology company to conduct human trials to test its COVID-19 vaccine in March. The trial includes 45 males and non-pregnant females aged 18 to 55.

Moderna’s vaccine utilizes the genetic sequence of the novel coronavirus. Basically, the goal is to build a vaccine out of messenger RNA.

Aside from Moderna, another biotech company called Curevac has been at the forefront of this cutting-edge technology.

In China, RNACure Biopharma has been working with Fudan University and Shanghai JiaoTong University on using the same technique to come up with a vaccine as well.

China’s CDC along with Tongji University and Stermina as well as Duke-NUS in partnership with Arcturus (ARCT) are also using a similar approach.

Although Moderna’s vaccine reached Phase 1 in record time, authorities cautioned that the development time frame is somewhere between 12 and 18 months — and this is even dubbed as an “overly optimistic” timeline.

Meanwhile, there are companies like Sanofi Pasteur (SNY) elected to use previously deployed vaccine platforms in earlier epidemics like SARS.

Johnson & Johnson (JNJ) also decided to employ the same strategy using its Ebola vaccine platform. In fact, JNJ shared that it’ll be ready to conduct human testing of its non-replicating viral vector by November.

Aside from JNJ, another biotechnology company in China called CanSino Biologics (HKG: 6185) in collaboration with the Academy of Military Medical Sciences is utilizing the same technology.

Just last week, Chinese authorities approved CanSino’s Phase 1 clinical trials.

Apart from JNJ and CanSino, other biotechnology companies are also working on a vaccine using the same non-replicating viral vector technology.

The list includes Wuhan’s BravoVax along with GeoVax (GOVX), Altimmune (ALT), Vaxart (VXRT), Greffex, and the University of Oxford.

Another strategy is employed by Novavax (NVAX), which is to construct a “recombinant” vaccine.

In a nutshell, this strategy entails extraction of the genetic code for the protein found on the Sars-CoV-2. This is a part of the virus that can trigger the immune system. This will then be pasted into the genome of a bacterium or yeast.

In effect, this vaccine will force the microorganisms to produce huge quantities of the protein to be able to fight off the virus.

 Big biotechnology companies like Sanofi and GlaxoSmithKline (GSK) are following the same technique.

Smaller firms are also in on the action including Generex Biotechnology Corporation (GNBT), Vaxil Bio (VXL.V), EpiVax, and Clover Biopharmaceuticals.

The University of Georgia, Baylor College of Medicine, and the University of Miami are pursuing the same lead as well.

On top of these, several biotechnology companies use a DNA-based approach to come up with a vaccine.

Last March 12, the Bill & Melinda Gates Foundation provided a $5 million grant to Pennsylvania-based biotech firm Inovio Pharmaceuticals (INO) to help the company speed up the tests needed for its DNA vaccine called INO-4800.

This is on top of the roughly $9 million in funding it received from the Coalition for Epidemic Preparedness Innovations earlier.

At the moment, INO-4800 is in preclinical studies with plans to push it to Phase 1 clinical trials by April.

Aside from Inovio, Applied DNA Sciences (APDN), Zydus Cadila (CADILAHC), Takis, and Evivax are also pursuing the same strategy.

Despite implementing the most effective and even draconian measures to contain COVID-19, these tactics only managed to slow down the spread of the virus.

With the World Health Organization tagging this situation as a pandemic, everyone has become more desperate in the search for a vaccine because only a vaccine can stop people from getting sick.

However, even the unprecedented speeds afforded, the biotechnology companies couldn’t change the fact that developing a vaccine requires at least a year. It’s crucial to not make mistakes along the way especially since the product could potentially be injected into most of the world’s population.

After all, there’s only a single thing that can be considered worse than a bad virus — and that is a bad vaccine.

 

 

 

 

 

 

 

vaccine

 

 

vaccine

 

vaccine

 

vaccine

 

vaccine

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-31 07:02:542020-06-28 14:09:47More Players Enter the Race for a Corona Cure
Mad Hedge Fund Trader

The Race to Find a Corona Cure

Biotech Letter

Naturally, many people are wondering about which stocks to own in light of the coronavirus. The latest development on the race to find a coronavirus cure is a joint effort involving two giant names from the biotechnology industry: Regeneron Pharmaceuticals (REGN) and Sanofi (SNY).

Taking a page off Gilead Sciences’ (GILD) move to recycle HIV drug Remdisivir and Roche Holding’s (ROG) decision to utilize rheumatoid arthritis Actemra, Sanofi and Regeneron are looking into an existing drug’s ability to offer refuge for patients suffering from COVID-19.

According to a recent announcement, the two companies are looking to test rheumatoid arthritis medication Kevzara on COVID-19 patients.

This drug was initially approved in 2017 and while it failed to reach blockbuster status at the time, Sanofi and Regeneron are preparing to transform it into the next leader in this pandemic race.

It should be noted though that Kevzara is not a coronavirus cure. Rather, the companies are hoping to use this drug to combat the symptoms related to COVID-19.

This is why it’s promising.

When a person gets infected by the novel coronavirus, the immune system is activated and starts attacking the virus to protect the body. As time passes, the immune system goes into overdrive and ends up overreacting, causing additional damage.

Gradually, the immune system starts attacking even the healthy tissue and organs as with the case for some COVID-19 patients.

This means that the coronavirus is causing an accelerated response from the immune system resulting in the patients’ damaged organs starting with the lungs.

This is where Kevzara comes in.

The drug functions as an inhibitor of the protein that triggers the patient’s immune and inflammatory response.

That is, Kevzara can stop the body from attacking itself despite the triggers caused by the coronavirus.

In terms of the specifics of this joint effort, Regeneron will take the lead for the US trials while Sanofi will be in charge of international efforts.

Aside from Kevzara, both Regeneron and Sanofi have been pursuing separate leads on how to deal with the pandemic.

Sanofi has been working in tandem with the US Department of Health and Human Services (HHS), specifically with the Biomedical Advanced Research and Development Authority (BARDA), to come up with a coronavirus vaccine. 

However, it’s the coronavirus efforts of Regeneron that gained much attention in the past weeks.

In February, Regeneron and the HHS expanded their partnership to come up with potential COVID-19 treatments. So far, the biotechnology giant has decided to work on monoclonal antibodies via its VelocImmune platform.

This avenue is particularly promising since Regeneron has already come up with an antiviral drug to combat Ebola. Its collaboration with HHS has also already resulted in plans to develop a MERS treatment, which is also a type of coronavirus.

According to Regeneron executives, the company will have a coronavirus treatment ready for human testing by August. If all goes well, then it aims to produce 200K prophylactic doses.

Although its innovative coronavirus proposals are exciting, Regeneron remains focused on its older and more dependable money makers particularly the eye drug Eylea.

This strength is in display in Regeneron’s fourth quarter results, which showed better than expected numbers.

For Eylea alone, the company generated an 11% year-over-year growth in sales.

Despite the emergence of new competitors like Novartis’ (NOVN) Beovu, Regeneron’s eye drug remains the leading product in this sector. In fact, Eylea managed to cross $2 billion in global sales just for the year 2019.

As for inflammation-reducer Dupixent, the treatment’s global sales climbed 136% in 2019.

Meanwhile, revenue from its cancer immunotherapy Libtayo soared to over quintuple from the previous period.

Building from the strength of Eylea, Regeneron also announced its successful late-stage clinical study that aimed to expand the indication of the drug to moderately severe to severe non-proliferative diabetic retinopathy (NPDR).

If this Eylea expansion pushes through, then Regeneron has yet another blockbuster drug in its hands.

In the past five years, Regeneron has demonstrated a strong EPS growth, growing by 23.74% annually. Given its recent performance and based on forward-looking statements, the company can be expected to report an average of 17.4% growth on its EPS in the next two years. 

Amid the panic and confusion caused by the coronavirus pandemic, it’s crucial to remain objective, especially with the stock market.

Before making a decision, ask yourself this question: “Will this current situation change the 10-year or even the 20-year outlook for the financial sector?” 

Despite the paranoia proliferating in the market in the past months, I believe the answer to this question is still a resounding “no.”

For now, it would be wise to treat owning stocks like how to own businesses. It's important to think about which stocks to own during the coronavirus, but don’t do it just to make a quick buck. Rather, take a look at lasting and stable companies with the capacity to not only grow over the years but also to compound their returns.

stocks to own during the coronavirus

 

stocks to own during the coronavirus

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-19 09:00:262020-04-26 23:01:30The Race to Find a Corona Cure
Mad Hedge Fund Trader

March 12, 2020

Biotech Letter

Mad Hedge Biotech & Healthcare Letter
March 12, 2020
Fiat Lux

Featured Trade:

(GILEAD SCIENCES’ CORONA BOOM)
(GILD), (FTSV), (SNY)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-12 09:02:442020-03-12 09:44:46March 12, 2020
Mad Hedge Fund Trader

Gilead Sciences' Corona Boom

Biotech Letter

The possibility of a pandemic is a terrifying thought. Nowadays though, you can’t switch on the news or surf the Internet without seeing reports about the worldwide spread of the coronavirus disease (COVID-19). Unfortunately, the fear that we once hoped to never be realized has become a reality.

The World Health Organization (WHO) has officially declared the coronavirus disease a pandemic.

The numbers are rising at an alarming speed, with over 1,300 confirmed cases in the United States alone and approximately 129,000 worldwide. As for the mortality rate, more than 4,700 people have died from this coronavirus disease.

Unsurprisingly, financial markets have taken a hit in recent weeks in response to the outbreak. The potential of an uncontrollable pandemic has wreaked havoc in the global economy instilling fear among investors.

With economists predicting that a full-scale pandemic could throw not only the US but also many developed countries into recession, the public has brace themselves for what lies ahead.

While a lot of companies are raking in profits enough to keep the wolf from the door, one biotechnology stock has been on a roll since the coronavirus outbreak went public: Gilead Sciences (GILD).

To date, Gilead has been hailed as possibly our best hope in discovering an effective treatment for the coronavirus.

Aside from being the first biotechnology stock to offer a solution to the outbreak, Gilead has another advantage over its rivals. It no longer has to start from scratch. Instead, the company reused Remdesivir, which is a drug it previously developed to cure Ebola but failed.

Basically, Remdesivir is designed as an antiviral drug that helps patients fight off viral infections. That means it targets not only the Ebola virus but also other types of viruses including SARS and MERS.

Since SARS and MERS are caused by the coronavirus as well, health experts believe that Remdesivir could be a treatment for COVID-19.

On January 31, doctors administered a dose of Remdesivir on a COVID-19 patient and discovered that the drug reversed almost all the major symptoms.

If Remdesivir proves to be the key to solving the COVID-19 outbreak, then Gilead will not only experience a massive performance boost but might even end up saving the world from a recession.

Despite this promising development, Gilead isn’t putting all its eggs in just one basket. 

The company has recently made its first major purchase in three years in the form of a $4.9 billion acquisition of cancer biotechnology company Forty Seven (FTSV) — approximately twice as much as the latter’s market cap.

Gilead’s main draw for this huge deal is FTSV’s promising lead pipeline candidate Magrolimab, which is a treatment that targets various types of cancer such as myelodysplastic syndrome and acute myeloid leukemia.

What sets apart Magrolimab is that it targets CD47, which is typically called the “don’t eat me signal” molecule that cancer cells utilize to circumvent the immune system.

Although Magrolimab is still in its trial phase, the treatment showed a notable 40% response rate for hard-to-treat blood cancers and 50% for Myelodysplastic syndrome. The drug is also getting tested for lymphoma and ovarian, bladder, and colorectal cancers.

This latest deal is in line with some of Gilead’s biggest acquisitions in recent years like its $11.9 billion deal with cancer immunotherapy developer Kite Pharma in 2017.

Apart from these, Gilead has expanded its $5 billion partnership with Galapagos (GLPG) in the hopes of finally bringing another blockbuster in its lineup.

The two have been working on  rheumatoid arthritis (RA) and Crohn's disease treatment Filgotinib, which has the potential to bring at least $1.3 billion in revenue in the next five years.

Once it hits the market, Magrolimab is expected to rake in $800 million to $1 billion in peak sales.

Although Gilead’s deal with Forty Seven has the highest price tag, it wasn’t the only acquisition of smaller immuno-oncology companies that happened recently. Merck (MRK) acquired AqQule for $2.7 billion while Sanofi (SNY) purchased Synthorx for $2.5 billion.

The COVID-19 pandemic has provided an unexpected opportunity for Gilead, and there’s no doubt that Remdesivir’s success will contribute to the company’s profits this year.

However, Gilead’s most promising growth driver is the rheumatoid arthritis lineup it’s developing with Galapagos. On top of these, it’s immuno-oncology pipeline is also shaping up to have some of the most exciting and promising candidates particularly for rare diseases.

The coronavirus pandemic has infused panic among the public, with more and more stocks getting dumped based on alarm and confusion. But as terrifying as this situation is, the best way to handle it is to remain calm and to put things in perspective.

Remember, solid companies will continuously achieve success in the long run no matter the temporary drawbacks in their stock prices. Buy those shares and simply hold on to them. Your future self will be grateful for that decision.

As fear continues to take over a lot of investors’ strategies, let me share with you one of my favorite pieces of advice from Warren Buffett: “Be fearful when others are greedy and be greedy when others are fearful.”

https://www.madhedgefundtrader.com/wp-content/uploads/2020/03/gilead.png 375 750 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2020-03-12 09:00:572020-03-12 09:44:30Gilead Sciences' Corona Boom
Mad Hedge Fund Trader

December 24, 2019

Biotech Letter

Mad Hedge Biotech & Healthcare Letter
December 24, 2019
Fiat Lux

Featured Trade:

(TAKING A SECOND LOOK AT SANOFI),
 (SNY), (NVO)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2019-12-24 06:02:252019-12-24 04:59:58December 24, 2019
Mad Hedge Fund Trader

Taking a Second Look at Sanofi

Biotech Letter

Investors on the lookout for a large-cap biotech investment have several options, with Sanofi SA (SNY) being one of the most interesting companies to consider. The French multinational pharma giant has a diverse drug portfolio which has been attracting attention recently thanks to its focus on the lucrative market of diabetes treatments.

Unfortunately, the diabetes project hasn’t been working as well as Sanofi hoped this year. Earlier in 2019, FDA rejected the company’s new diabetes candidate Zynquista. Despite this setback, the company announced more promising Phase 3 results from another diabetes treatment, Toujeo, which is aimed at children and adolescents with Type 1 diabetes.

Regardless of the roadblocks encountered by Sanofi in its bid to dominate this lucrative market, the company has been insistent in this endeavor -- a determination that’s actually pretty understandable given that the diabetes market covers over 425 million people worldwide.

So far, Sanofi has managed to be one of the leaders in this sector, with insulin injection pen Lantus working as a stable revenue driver for the biopharma for years now.

To offer a clearer perspective on the promising diabetes sector, Lantus raked in $3.95 billion in sales for 2018 alone -- an impressive growth that has been attracting competitors left and right.

In fact, this Sanofi diabetes moneymaker has been experiencing steep competition with sales slipping by over $1.17 billion largely due to the emergence of cheaper and stronger rivals in the market.

Nonetheless, Sanofi wants to maintain its stronghold so new deals are expected to crop up soon in an effort to shore up its declining Lantus revenue. Among the drugs in its portfolio, Toujeo has actually been doing quite well, raking in $930 million in sales in 2018. While this doesn’t really cover the $1.17 billion slip from Lantus sales over the same period, the figure is close enough to bring hope to investors and keep competitors at bay.

Sanofi’s strongest competitor, particularly in the diabetes market, is Novo Nordisk (NVO). The latter’s diabetes drug Tresiba has actually accounted for 84.2% of its overall sales.

While this is definitely daunting for Sanofi, the sales performance of Tresiba can also highlight a key differentiator between the two. That is, Sanofi offers a more diversified portfolio especially in terms of revenue sources. Meanwhile, Novo Nordisk is focused on the diabetes market alone.

Although both Toujeo and Lantus have been remarkable in sales thus far, Sanofi has a number of other top-performing drugs in its portfolio. After all, Sanofi isn’t just about diabetes treatments.

In terms of growth, eczema treatment Dupixent has shown a remarkable 142% jump in sales over the past year. Its revenues rose to $628 million for the third quarter in 2019. In comparison, the overall sales for Sanofi’s diabetes treatments declined by 18% since the third quarter of 2018. 

While it’s easy to get distracted by the allure of the lucrative diabetes market, these treatments actually comprise a small portion of the French biopharma’s drug portfolio.

To date, Sanofi has 85 up-and-coming drugs, with 51 of these already sent to early clinical tests and the remaining 34 either in Phase 3 trials or sent for approvals. To provide a more direct comparison, reports show that only two drugs in the pipeline are aimed towards the diabetes market. The rest of Sanofi’s portfolio has 28 oncology candidates and 18 immuno-inflammation drug prospects.

Overall, Sanofi has a stable, well-rounded portfolio to offer its investors. However, stiff competition can prove to be a huge obstacle especially in the high-growth diabetes space. Its revenue growth in this sector isn’t also as remarkable as its competitors.

This doesn’t take away from Sanofi’s other products though. What it means is that it would be a better call to buy Sanofi stock once prices fall at a cheaper valuation.

https://www.madhedgefundtrader.com/wp-content/uploads/2019/12/sanofi-1.png 252 485 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2019-12-24 06:00:232019-12-24 05:00:09Taking a Second Look at Sanofi
Mad Hedge Fund Trader

December 10, 2019

Biotech Letter

Mad Hedge Biotech & Healthcare Letter
December 10, 2019
Fiat Lux

Featured Trade:

(SANOFI’S RETREAT FROM THE DIABETES MARKET),
(SNY), (NVO)

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