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Mad Hedge Fund Trader

The Biggest News in Biotech Today

Biotech Letter

It’s not typical for stock market news to alter the lives of millions of people across the globe, but this is what Biogen (BIIB) managed to accomplish this week.

The company received accelerated approval from the US Food and Drug Administration (FDA) for its controversial Alzheimer’s disease treatment, Aducanumab.

The drug, which is now marketed as Aduhelm, marks a potential breakthrough medication for over 6 million Americans suffering from the debilitating illness and to possibly billions all worldwide.  

Basically, Aduhelm targets what Biogen calls “a defining pathology of the disease” by decreasing the amyloid beta plaque levels in the brains of patients suffering from Alzheimer’s disease.

Biogen shares spiked by roughly 60% following the Aduhelm news, with the pop in the biotechnology stock even more impressive than what was initially predicted.

This latest FDA approval also brings a ray of hope for the biotechnology industry.

Biotech shares have been in a slump this year, with the SPDR S&P Biotech ETF (XBI) falling by 9.2% thus far.

Potential second-order effects of the Biogen win can easily be seen in other developers of Alzheimer’s disease treatments.

Although the moves may not be as dramatic as Biogen’s, several biotech companies benefited from the good news.

Directly benefiting from it is Japanese drugmaker Eisai (ESALY), which has been working with Biogen on Alzheimer’s disease treatment. This company’s American depository receipts climbed by 48.2% after the news broke.

Eli Lilly (LLY), which is also working on its own Alzheimer’s therapy, saw its shares go up 9.3%.

Even Roche (RHHBY), which is still in the early stages of its development of a similar treatment, enjoyed a 1.6% increase, while an under-the-radar biotech company, Denali Therapeutics (DNLI), experienced a 7.8% increase.

Other smaller companies that benefited from Biogen’s news include Sarepta Therapeutics (SRPT), Ionis Pharmaceuticals (IONS), Intercept Pharmaceuticals (ICPT), Cassava Sciences (SAVA), and Annovis Bio (ANVS).

In terms of pricing, Aduhelm is estimated to cost $56,000 per year.

Although there is still no definite number in terms of how much Aduhelm could generate in sales for the company, there have been early estimates prior to this news.

Before this accelerated approval, Aduhelm was projected to add at least $16 billion in market capitalization to Biogen.

If successful, the drug can contribute a minimum of $10 billion in sales annually—a performance that would make Aduhelm one of the best-selling drugs of all time. 

At this price point as well, the drug could peak at $5.7 billion by 2027.

Understanding that the cost is too high for some, Biogen has been working on establishing partnerships with healthcare and insurance companies to help patients cover the expenses.

So far, Biogen has been negotiating with Cigna (CI) to come up with terms to make Aduhelm available to Alzheimer’s patients via a value-based contract.

That is, the pricing will be assessed based on how responsive the patient will be to the treatment.

Biogen has also been working on collaborating with CVS Health (CVS) to develop more efficient ways to implement cognitive screenings in urban markets.

The two companies have been looking into boosting testing within underserved communities to improve early diagnosis, with the project commencing by September.

Some cities included in this initiative are Washington, D.C., Los Angeles, Dallas, Chicago, South Carolina, Atlanta, New York, Detroit, and Philadelphia.

Biogen has finally regained its momentum thanks to this accelerated and unprecedented approval.

That means we can expect Biogen to leverage this massive revenue stream to round out the rest of its programs and boost its R&D, as well as possibly compensating its shareholders with share buybacks and even dividends in the second half of this decade.

 

aduhelm

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-08 15:00:312021-06-13 15:27:16The Biggest News in Biotech Today
Mad Hedge Fund Trader

Trade Alert - (AMZN) June 8, 2021 - SELL-TAKE PROFITS

Tech Alert

When John identifies a strategic exit point, he will send you an alert with specific trade information as to what security to sell, when to sell it, and at what price. Most often, it will be to TAKE PROFITS, but, on rare occasions, it will be to exercise a STOP LOSS at a predetermined price to adhere to strict risk management discipline. Read more

https://www.madhedgefundtrader.com/wp-content/uploads/2016/02/Alert-e1457452190575.jpg 135 150 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-08 10:27:112021-06-08 10:27:11Trade Alert - (AMZN) June 8, 2021 - SELL-TAKE PROFITS
Mad Hedge Fund Trader

June 8, 2021

Diary, Newsletter, Summary

Global Market Comments
June 8, 2021
Fiat Lux

Featured Trade:

(MEET THE GREEKS)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-08 09:04:172021-06-08 09:27:32June 8, 2021
Mad Hedge Fund Trader

June 7, 2021

Tech Letter

Mad Hedge Technology Letter
June 7, 2021
Fiat Lux

Featured Trade:

(THE CIRCUSIFICATION OF TEHC STOCKS)
(TSLA), (GME), (RH), (BTC), (ETH)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 15:04:552021-06-07 15:47:53June 7, 2021
Mad Hedge Fund Trader

The Circusification of Tech Stocks

Tech Letter

The younger U.S. generations went from almost not knowing what the stock market was to overnight dominance of it.

They now make the rules.

Millions of new brokerage accounts have been wielded since the start of the pandemic.

Trillions in value transferred from taxpayers and the Federal Reserve into brokerage accounts at Robinhood and Coinbase.

More dollar bills are funneled into these accounts with every paycheck.

The stock market and the generations above it are still trying to figure out what just happened.

Leverage is another thing this generation Googled and figured out how to harness too during the pandemic.

This generation is truly fearless, or they haven’t been trading long enough to understand what it feels like to lose all your money.

It doesn’t matter because the only thing that matters is what they pay attention to and what’s irrelevant.

If they choose to prop up a 10-word Elon Musk tweet into bulletproof trading strategies, how will you stop them?

If they want Gamestop (GME) to go from $17 before the pandemic to $270 today with even this morning trading in it up 10%, how do you stop something like this?

The answer is you can’t.

How do you convince newly minted investors that diversification makes sense when the first stock they ever bought, Tesla (TSLA), rose 800% while everything else barely moved?

Generations before what is going on now, investors held a series of adages near and dear to them.

Every generation puts its own spin on trading, but what we are witnessing today is that rules are not important anymore when the pace of technology changes every industry to the point that these industries are now unrecognizable.

The new rules mean there are no rules anymore and that’s the beauty or hideous side of investing now, whether you like it or not.

It used to be that “serious” investors religiously followed value investing, which was pioneered by Benjamin Graham and the U.S. emerged from the Great Depression, and his two seminal books were investment bibles.

1934’s Security Analysis and 1949’s The Intelligent Investor laid the groundwork for a generation of contrarian investors who eschewed macroeconomic trends and market patterns, and instead focused on a company’s fundamentals, looking for cheap stocks that they would hold for 20 or even 30 years.

Legends such as Irving Kahn, John Templeton, and Warren Buffett have made value investing synonymous with successful investing for decades.

Now these people who held up these books as bibles can’t understand markets.

They have seen bull and bear markets or all sorts, but nothing like this before.

We locked everyone in their homes for a year and gave them a virtual life to live on their screens.

Why should we be surprised if younger generations treat money and investments like tokens in a video game?

If you had opened your first brokerage account in the spring of 2020, you would most likely have opened it at Robinhood.

You downloaded an app, transferred $500 in from your couch, and pressed some buttons and looked at the screen with some digital numbers that said you had a nice profit.  

With a Robinhood account, your first exposure to cryptocurrencies does not frame them as an unproven alternative to stocks. The two stand on equal footing.

This is radically different from the experience of the Gen X and boomer investors logging in through Schwab, Fidelity, or Vanguard to check their balances or download a statement.

What we are seeing is that a new generation is creating the new conventions of the investing landscape and views stocks and crypto coins as interchangeable with equal credibility.

Now every prominent news site is leading with crypto news more often than not and ad platforms like Twitter have said that crypto ads are their highest growth product.  

This phenomenon is here to stay because the same will go for any young investor that opens up the incremental brokerage account to trade from their phone tomorrow and the next day after that.

These people are taking profits from Tesla and rolling them into trades like Dogecoin, Ethereum (ETH), and Bitcoin (BTC).

This behavior is starting to become normalized and positive liquidity event in alternative assets will spawn more volume trading in these very assets that were called as “toxic” and a “scam.”

The laughable thing is just one of the 48 U.S.-listed stocks in Berkshire Hathaway portfolio, consumer discretionary RH (RH), topped the price gains of Bitcoin over the past 12 months.

Therefore, don’t ask this generation about the annual average returns of the “safe” 60/40 stock-and-bond portfolios touted by planners and advisers.

Don’t ask this generation to read the Intelligent Investor because it’s outdated. Assets aren’t trading on fundamentals anymore and the Fed printing money like it's their job is fueling a massive tidal wave of new capital into crypto like it's not even funny.  

It doesn’t make sense anymore to the Warren Buffets and Charles Munger.

When asked about Bitcoin directly at the Berkshire Hathaway's annual shareholders meeting earlier this month in Los Angeles, he said “I'm going to dodge that question.”  

And now, it’s expanded into the exurbs to include blank-check companies, venture-backed startups, tradable bits of computer code, and investable software protocols.

Your father’s stock market is never coming back and the one from before the pandemic isn’t coming either.

The stock market is still one of the only games in town which makes it hard to avoid for any American who prioritizes wealth accumulation.

The pandemic leveled the playing field for crypto and they used that new oxygen to mint many new millionaires and billionaires who now harness capital that has the potential to be reinvested into the asset landscape.

If it’s turned into a 3-ring circus because of a fusional 1-off event, then better figure out how this new circus works earlier than later.

investing

 

investing

 

investing

 

https://www.madhedgefundtrader.com/wp-content/uploads/2021/06/bitcoin-jun7.png 772 936 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 15:02:272021-06-13 15:07:20The Circusification of Tech Stocks
Mad Hedge Fund Trader

June 7, 2021 - Quote of the Day

Tech Letter

“Getting information off the Internet is like taking a drink from a fire hydrant.” – Said American Entrepreneur Mitch Kapor

https://www.madhedgefundtrader.com/wp-content/uploads/2021/06/mitch-kapor.png 436 304 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 15:00:222021-06-07 15:46:25June 7, 2021 - Quote of the Day
Mad Hedge Fund Trader

June 7, 2021

Diary, Newsletter, Summary

Global Market Comments
June 7, 2021
Fiat Lux

Featured Trade:

(MAD HEDGE TRADERS & INVESTORS SUMMIT JUNE 8-10)
(LEARNING THE ART OF RISK CONTROL)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 09:06:052021-06-07 17:22:43June 7, 2021
Mad Hedge Fund Trader

Mad Hedge Traders & Investors Summit June 8-10

Diary, Newsletter

Come Join John Thomas, the Mad Hedge Fund Trader, for his Traders & Investors Summit from Tuesday, June 8 to Thursday, June 10, 2021.

John has spent the last 50 years looking for the top traders and investors in the industry. Now you can meet the people he has found, the best of the best, cream of the crop.

These are incredibly talented individuals who can make money in any market conditions, including during a Covid-19 pandemic and the resulting stock market melt-up.

It really is a smorgasbord of successful trading strategies from which you can pick and choose at your leisure.

Listening to these speakers will change your life.

Best of all, attendance is FREE.

To sign up, please click here.

 

Thank you!

 

https://www.madhedgefundtrader.com/wp-content/uploads/2021/06/Q2summit.png 628 864 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 09:04:242021-06-07 17:26:02Mad Hedge Traders & Investors Summit June 8-10
Mad Hedge Fund Trader

June 7, 2021 - Quote of the Day

Diary, Newsletter, Quote of the Day

The market has gone from “Buy the dip and sell the rip” to “Buy the dip and buy the rip,” said Dennis Dick, a professional trader.

https://www.madhedgefundtrader.com/wp-content/uploads/2020/06/trading.png 174 289 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-07 09:00:582021-06-07 12:30:50June 7, 2021 - Quote of the Day
Mad Hedge Fund Trader

June 4, 2021

Tech Letter

Mad Hedge Technology Letter
June 4, 2021
Fiat Lux

Featured Trade:

(RIDING THE COATTAILS OF ELLIOT MANAGEMENT)
(DBX), (TWTR), (EBAY), (CRM), (BOX)

https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png 0 0 Mad Hedge Fund Trader https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png Mad Hedge Fund Trader2021-06-04 13:04:222021-06-07 10:45:46June 4, 2021
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Legal Disclaimer

There is a very high degree of risk involved in trading. Past results are not indicative of future returns. MadHedgeFundTrader.com and all individuals affiliated with this site assume no responsibilities for your trading and investment results. The indicators, strategies, columns, articles and all other features are for educational purposes only and should not be construed as investment advice. Information for futures trading observations are obtained from sources believed to be reliable, but we do not warrant its completeness or accuracy, or warrant any results from the use of the information. Your use of the trading observations is entirely at your own risk and it is your sole responsibility to evaluate the accuracy, completeness and usefulness of the information. You must assess the risk of any trade with your broker and make your own independent decisions regarding any securities mentioned herein. Affiliates of MadHedgeFundTrader.com may have a position or effect transactions in the securities described herein (or options thereon) and/or otherwise employ trading strategies that may be consistent or inconsistent with the provided strategies.

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