Another year, another set of challenges and opportunities for investors. How can you make sure that you’re starting the year right?
If you’re looking to dip your toe in the biotechnology and healthcare sector, it won’t hurt to look at what the experts, such as Warren Buffett, are doing.
With a 55-year track record of 21% in annual returns for its Berkshire (BRK.B) investors, I’d say the Oracle of Omaha definitely knows his craft.
One of his most famous pieces of advice is to buy “wonderful companies at fair prices,” and I think this pearl of wisdom perfectly fits Buffett’s favored high-yield aristocrat: AbbVie (ABBV).
More interestingly, AbbVie is currently undervalued primarily due to overblown fears of patent loss for its top-selling drug Humira in 2023 and another in 2026 for Imbruvica.
Admittedly, the anxiety of investors is not entirely unfounded.
After all, AbbVie must replenish roughly $20 billion worth of annual revenue from Humira alone in the following years as the drug loses its patents and faces declining sales.
Obviously, losing revenue from a primary growth driver could be a massive problem for any company.
It could even lead to stagnating numbers in the next couple of years — a situation that the likes of Gilead Sciences (GILD), despite its $90.58 market capitalization, have become all too familiar.
Nevertheless, AbbVie isn’t simply twiddling its thumbs, waiting for the inevitable patent loss to happen.
The company has been busy preparing for the Humira and Imbruvica patent cliffs. In fact, it has been working to diversify its portfolio steadily.
One of the steps it undertook was to leverage its cash flow and $238.35 billion market capitalization to boost its R&D.
This led to AbbVie holding one of the industry’s most robust pipelines to date.
Some of the most promising products in its portfolio are Humira successors Skyrizi and Rinvoq.
Together, these two treatments are estimated to generate more than $15 billion in sales by 2025.
And AbbVie isn’t done yet.
Following its wildly successful formula in Humira, AbbVie is also looking into expanding the indications for the drug’s successors.
So far, Rinvoq has been able to deliver on this promise. Recently, this Humira successor has received FDA approval as a second-line treatment for psoriatic arthritis.
With this second indication, more and more investors are starting to believe that AbbVie has yet another blockbuster in the making.
Let’s look at the market for Rinvoq’s latest indication.
In the US alone, there are approximately 1 million to 2 million patients of psoriatic arthritis. For simplicity’s sake, let’s just say that there are 1.5 million patients in the US.
Generally, the first-line of treatment typically fails for 20% of psoriatic arthritis patients. That leads to roughly 300,000 patients who would be in need of second-line treatment.
For the sake of accuracy, it’s vital to point out that there are already a number of psoriatic arthritis treatments available in the US, such as Otezla and Enbrel from Amgen (AMGN). Moreover, JAK inhibitors are still facing potential restrictions from the FDA, thanks to the issue with Pfizer (PFE).
So, we can conservatively say that AbbVie’s Rinvoq might only be able to capture an estimated 7% of the psoriatic arthritis market share.
This translates to approximately 21,000. The annual list price for Rinvoq is at $63,000.
Taking into consideration the negotiation tactics of health insurers for price adjustments, the drug might go down to an annual list price of $44,000 instead.
Based on these conservative assumptions, Rinvoq would rake in sales of over $900 million—falling only slightly below the $1 billion blockbuster mark.
While this only hits less than 2% of AbbVie’s anticipated $56.2 billion annual revenue, this trajectory is a massive success for Rinvoq.
Bear in mind that this Humira successor has been on track to generate over $1.5 billion in sales in 2021.
Hence, adding $900 million from its psoriatic arthritis indication would offer a whopping more than 60% jump in its annual revenue.
Considering its history and trajectory, AbbVie is expected to continue to outshine its rivals in the industry.
Actually, the growth consensus for this stock is at 4% to 6.5%.
While that does not sound very impressive, it’s important to remember that the long-term growth rate for the whole industry is only 4%.
That easily puts AbbVie ahead of at least 63% of its peers in terms of growth.
Aside from the fact that this blue-chip stock is an excellent way to enjoy a solid 4.3% yield these days, the company is proving to be effective in ensuring that it delivers market-beating returns in the long run.
Needless to say, AbbVie qualifies as a classic “wonderful company at a fair price.”
https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png00Mad Hedge Fund Traderhttps://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.pngMad Hedge Fund Trader2022-01-06 13:00:022022-01-15 15:38:28A Wonderful Company at a Fair Price
I am once again writing this report from a first-class sleeping cabin on Amtrak’s legendary California Zephyr.
By day, I have two comfortable seats facing each other next to a panoramic window. At night, they fold into two bunk beds, a single and a double. There is a shower, but only Houdini could navigate it.
I am anything but Houdini, so I go downstairs to use the larger public hot showers. They are divine.
We are now pulling away from Chicago’s Union Station, leaving its hurried commuters, buskers, panhandlers, and majestic great halls behind. I love this building as a monument to American exceptionalism.
I am headed for Emeryville, California, just across the bay from San Francisco, some 2,121.6 miles away. That gives me only 56 hours to complete this report.
I tip my porter, Raymond, $100 in advance to make sure everything goes well during the long adventure and to keep me up-to-date with the onboard gossip. The rolling and pitching of the car is causing my fingers to dance all over the keyboard. Microsoft’s Spellchecker can catch most of the mistakes, but not all of them.
As both broadband and cell phone coverage are unavailable along most of the route, I have to rely on frenzied Internet searches during stops at major stations along the way to Google obscure data points and download the latest charts.
You know those cool maps in the Verizon stores that show the vast coverage of their cell phone networks? They are complete BS.
Who knew that 95% of America is off the grid? That explains so much about our country today.
I have posted many of my better photos from the trip below, although there is only so much you can do from a moving train and an iPhone 12X pro.
Here is the bottom line which I have been warning you about for months. In 2022, you are going to have to work twice as hard to earn half as much money with double the volatility.
It’s not that I’ve turned bearish. The cause of the next bear market, a recession, is at best years off. However, we are entering the third year of the greatest bull market of all time. Expectations have to be toned down and brought back to earth. Markets will no longer be so strong that they forgive all mistakes, even mine.
2022 will be a trading year. Play it right, and you will make a fortune. Get lazy and complacent and you’ll be lucky to get out with your skin still attached.
If you think I spend too much time absorbing conspiracy theories or fake news from the Internet, let me give you a list of the challenges I see financial markets are facing in the coming year:
The Ten Key Variables for 2022
1) How soon will the Omicron wave peak?
2) Will the end of the Fed’s quantitative easing knock the wind out of the bond market?
3) Will the Russians invade the Ukraine or just bluster as usual?
4) How much of a market diversion will the US midterm elections present?
5) Will technology stocks continue to dominate, or will domestic recovery, and value stocks take over for good?
6) Can the commodities boom get a second wind?
7) How long will the bull market for the US dollar continue?
8) Will the real estate boom continue, or are we headed for a crash?
9) Has international trade been permanently impaired or will it recover?
10) Is oil seeing a dead cat bounce or is this a sustainable recovery?
The Thumbnail Portfolio
Equities – buy dips Bonds – sell rallies Foreign Currencies – stand aside Commodities – buy dips Precious Metals – stand aside Energy – stand aside Real Estate – buy dips Bitcoin – Buy dips
1) The Economy
What happens after a surprise variant takes Covid cases to new all-time highs, the Fed tightens, and inflation soars?
Covid cases go to zero, the Fed flip flops to an ease and inflation moderates to its historical norm of 3% annually.
It all adds up to a 5% US GDP growth in 2022, less than last year’s ballistic 7% rate, but still one of the hottest growth rates in history.
If Joe Biden’s build-back batter plan passes, even in diminished form, that could add another 1%.
Once the supply chain chaos resolves inflation will cool. But after everyone takes delivery of their over orders conditions could cool.
This sets up a Goldilocks economy that could go on for years: high growth, low inflation, and full employment. Help wanted signs will slowly start to disappear. A 3% handle on Headline Unemployment is within easy reach.
The weak of heart may want to just index and take a one-year cruise around the world instead in 2022 (here's the link for Cunard).
So here is the perfect 2022 for stocks. A 10% dive in the first half, followed by a rip-roaring 20% rally in the second half. This will be the year when a big rainy-day fund, i.e., a mountain of cash to spend at market bottoms, will be worth its weight in gold.
That will enable us to load up with LEAPS at the bottom and go 100% invested every month in H2.
That should net us a 50% profit or better in 2022, or about half of what we made last year.
Why am I so cautious?
Because for the first time in seven years we are going to have to trade with a headwind of rising interest rates. However, I don’t think rates will rise enough to kill off the bull market, just give traders a serious scare.
The barbell strategy will keep working. When rates rise, financials, the cheapest sector in the market, will prosper. When they fall, Big Tech will take over, but not as much as last year.
The main support for the market right now is very simple. The investors who fell victim to capitulation selling that took place at the end of November never got back in. Shrinking volume figures prove that. Their efforts to get back in during the new year could take the S&P 500 as high as $5,000 in January.
After that the trading becomes treacherous. Patience is a virtue, and you should only continue new longs when the Volatility Index (VIX) tops $30. If that means doing nothing for months so be it.
We had four 10% corrections in 2021. 2022 will be the year of the 10% correction.
Energy, Big Tech, and financials will be the top-performing sectors of 2022. Big Tech saw a 20% decline in multiples in 2022 and will deliver another 30% rise in earnings in 2022, so they should remain at the core of any portfolio.
It will be a stock pickers market. But so was 2021, with 51% of S&P 500 performance coming from just two stocks, Tesla (TSLA) and Alphabet (GOOGL).
However, they are already so over-owned that they are prone to dead periods as long as eight months, as we saw last year. That makes a multipronged strategy essential.
Amtrak needs to fill every seat in the dining car to get everyone fed on time, so you never know who you will share a table with for breakfast, lunch, and dinner.
There was the Vietnam Vet Phantom Jet Pilot who now refused to fly because he was treated so badly at airports. A young couple desperately eloping from Omaha could only afford seats as far as Salt Lake City. After they sat up all night, I paid for their breakfast.
A retired British couple was circumnavigating the entire US in a month on a “See America Pass.” Mennonites are returning home by train because their religion forbade automobiles or airplanes.
The national debt ballooned to an eye-popping $30 trillion in 2021, a gain of an incredible $3 trillion and a post-World War II record. Yet, as long as global central banks are still flooding the money supply with trillions of dollars in liquidity, bonds will not fall in value too dramatically. I’m expecting a slow grind down in prices and up in yields.
The great bond short of 2021 never happened. Even though bonds delivered their worst returns in 19 years, they still remained nearly unchanged. That wasn’t good enough for the many hedge funds, which had to cover massive money-losing shorts into yearend.
Instead, the Great Bond Crash will become a 2022 business. This time, bonds face the gale force headwinds of three promised interest rates hikes. The year-end government bond auctions were a complete disaster.
Fed borrowing continues to balloon out of control. It’s just a matter of time before the last billion dollars in government borrowing breaks the camel’s back.
That makes a bond short a core position in any balanced portfolio. Don’t get lazy. Make sure you only sell a rally lest we get trapped in a range, as we did for most of 2021.
For the first time in ages, I did no foreign exchange trades last year. That is a good thing because I was wrong about the direction of the dollar for the entire year.
Sometimes, passing on bad trades is more important than finding good ones.
I focused on exploding US debt and trade deficits undermining the greenback and igniting inflation. The market focused on delta and omicron variants heralding new recessions. The market won.
The market won’t stay wrong forever. Just as bond crash is temporarily in a holding pattern, so is a dollar collapse. When it does occur, it will happen in a hurry.
5) Commodities (FCX), (VALE), (DBA)
The global synchronized economic recovery now in play can mean only one thing, and that is sustainably higher commodity prices.
The twin Covid variants put commodities on hold in 2021 because of recession fears. So did the Chinese real estate slowdown, the world’s largest consumer of hard commodities.
The heady days of the 2011 commodity bubble top are now in play. Investors are already front running that move, loading the boat with Freeport McMoRan (FCX), US Steel (X), and BHP Group (BHP).
Now that this sector is convinced of an eventual weak US dollar and higher inflation, it is once more the apple of traders’ eyes.
China will still demand prodigious amounts of imported commodities once again, but not as much as in the past. Much of the country has seen its infrastructure build out, and it is turning from a heavy industrial to a service-based economy, like the US. Investors are keeping a sharp eye on India as the next major commodity consumer.
And here’s another big new driver. Each electric vehicle requires 200 pounds of copper and production is expected to rise from 1 million units a year to 25 million by 2030. Annual copper production will have to increase 11-fold in a decade to accommodate this increase, no easy task, or prices will have to ride.
The great thing about commodities is that it takes a decade to bring new supply online, unlike stocks and bonds, which can merely be created by an entry in an excel spreadsheet. As a result, they always run far higher than you can imagine.
Accumulate commodities on dips.
Snow Angel on the Continental Divide
6) Energy (DIG), (RIG), (USO), (DUG), (UNG), (USO), (XLE), (AMLP)
Energy may be the top-performing sector of 2022. But remember, you will be trading an asset class that is eventually on its way to zero.
However, you could have several doublings on the way to zero. This is one of those times.
The real tell here is that energy companies are drinking their own Kool-Aid. Instead of reinvesting profits back into their new exploration and development, as they have for the last century, they are paying out more in dividends.
There is the additional challenge in that the bulk of US investors, especially environmentally friendly ESG funds, are now banned from investing in legacy carbon-based stocks. That means permanently cheap valuations and shares prices for the energy industry.
Energy stocks are also massively under-owned, making them prone to rip-you-face-off short squeezes. Energy now counts for only 3% of the S&P 500. Twenty years ago it boasted a 15% weighting.
The gradual shut down of the industry makes the supply/demand situation more volatile. Therefore, we could top $100 a barrel for oil in 2022, dragging the stocks up kicking and screaming all the way.
Unless you are a seasoned, peripatetic, sleep-deprived trader, there are better fish to fry.
The train has added extra engines at Denver, so now we may begin the long laboring climb up the Eastern slope of the Rocky Mountains.
On a steep curve, we pass along an antiquated freight train of hopper cars filled with large boulders.
The porter tells me this train is welded to the tracks to create a windbreak. Once, a gust howled out of the pass so swiftly, that it blew a passenger train over on its side.
In the snow-filled canyons, we saw a family of three moose, a huge herd of elk, and another group of wild mustangs. The engineer informs us that a rare bald eagle is flying along the left side of the train. It’s a good omen for the coming year.
We also see countless abandoned 19th century gold mines and the broken-down wooden trestles leading to them, relics of previous precious metals booms. So, it is timely here to speak about the future of precious metals.
Fortunately, when a trade isn’t working, I avoid it. That certainly was the case with gold last year.
2021 was a terrible year for precious metals. With inflation soaring, stocks volatile, and interest rates going nowhere, gold had every reason to rise. Instead, it fell for almost all of the entire year.
Bitcoin stole gold’s thunder, sucking in all of the speculative interest in the financial system. Jewelry and industrial demand was just not enough to keep gold afloat.
This will not be a permanent thing. Chart formations are starting to look encouraging, and they certainly win the price for a big laggard rotation. So, buy gold on dips if you have a stick of courage on you.
Would You Believe This is a Blue State?
8) Real Estate (ITB), (LEN)
The majestic snow-covered Rocky Mountains are behind me. There is now a paucity of scenery, with the endless ocean of sagebrush and salt flats of Northern Nevada outside my window, so there is nothing else to do but write.
My apologies in advance to readers in Wells, Elko, Battle Mountain, and Winnemucca, Nevada.
It is a route long traversed by roving banks of Indians, itinerant fur traders, the Pony Express, my own immigrant forebearers in wagon trains, the transcontinental railroad, the Lincoln Highway, and finally US Interstate 80, which was built for the 1960 Winter Olympics at Squaw Valley.
Passing by shantytowns and the forlorn communities of the high desert, I am prompted to comment on the state of the US real estate market.
There is no doubt a long-term bull market in real estate will continue for another decade, although from here prices will appreciate at a 5%-10% slower rate.
There is a generational structural shortage of supply with housing which won’t come back into balance until the 2030s.
There are only three numbers you need to know in the housing market for the next 20 years: there are 80 million baby boomers, 65 million Generation Xer’s who follow them, and 86 million in the generation after that, the Millennials.
The boomers have been unloading dwellings to the Gen Xers since prices peaked in 2007. But there are not enough of the latter, and three decades of falling real incomes mean that they only earn a fraction of what their parents made. That’s what caused the financial crisis.
If they have prospered, banks won’t lend to them. Brokers used to say that their market was all about “location, location, location.” Now it is “financing, financing, financing.” Imminent deregulation is about to deep-six that problem.
There is a happy ending to this story.
Millennials now aged 26-44 are now the dominant buyers in the market. They are transitioning from 30% to 70% of all new buyers of homes.
The Great Millennial Migration to the suburbs and Middle America has just begun. Thanks to Zoom, many are never returning to the cities. So has the migration from the coast to the American heartland.
That’s why Boise, Idaho was the top-performing real estate market in 2021, followed by Phoenix, Arizona. Personally, I like Reno, Nevada, where Apple, Google, Amazon, and Tesla are building factories as fast as they can.
As a result, the price of single-family homes should rocket during the 2020s, as they did during the 1970s and the 1990s when similar demographic forces were at play.
This will happen in the context of a coming labor shortfall, soaring wages, and rising standards of living.
Rising rents are accelerating this trend. Renters now pay 35% of their gross income, compared to only 18% for owners, and less, when multiple deductions and tax subsidies are taken into account. Rents are now rising faster than home prices.
Remember, too, that the US will not have built any new houses in large numbers in 13 years. The 50% of small home builders that went under during the crash aren’t building new homes today.
We are still operating at only a half of the peak rate. Thanks to the Great Recession, the construction of five million new homes has gone missing in action.
That makes a home purchase now particularly attractive for the long term, to live in, and not to speculate with.
You will boast to your grandchildren how little you paid for your house, as my grandparents once did to me ($3,000 for a four-bedroom brownstone in Brooklyn in 1922), or I do to my kids ($180,000 for a two-bedroom Upper East Side Manhattan high rise with a great view of the Empire State Building in 1983).
That means the major homebuilders like Lennar (LEN), Pulte Homes (PHM), and KB Homes (KBH) are a buy on the dip.
Quite honestly, of all the asset classes mentioned in this report, purchasing your abode is probably the single best investment you can make now. It’s also a great inflation play.
If you borrow at a 3.0% 30-year fixed rate, and the long-term inflation rate is 3%, then, over time, you will get your house for free.
How hard is that to figure out? That math degree from UCLA is certainly earning its keep.
Crossing the Bridge to Home Sweet Home
9) Bitcoin
It’s not often that new asset classes are made out of whole cloth. That is what happened with Bitcoin, which, in 2021, became a core holding of many big institutional investors.
But get used to the volatility. After doubling in three months, Bitcoin gave up all its gains by year-end. You have to either trade Bitcoin like a demon or keep your positions so small you can sleep at night.
By the way, right now is a good place to establish a new position in Bitcoin.
10) Postscript
We have pulled into the station at Truckee in the midst of a howling blizzard.
My loyal staff has made the ten-mile trek from my beachfront estate at Incline Village to welcome me to California with a couple of hot breakfast burritos and a chilled bottle of Dom Perignon Champagne, which has been resting in a nearby snowbank. I am thankfully spared from taking my last meal with Amtrak.
After that, it was over legendary Donner Pass, and then all downhill from the Sierras, across the Central Valley, and into the Sacramento River Delta.
Well, that’s all for now. We’ve just passed what was left of the Pacific mothball fleet moored near the Benicia Bridge (2,000 ships down to six in 50 years). The pressure increase caused by a 7,200-foot descent from Donner Pass has crushed my plastic water bottle. Nice science experiment!
The Golden Gate Bridge and the soaring spire of Salesforce Tower are just around the next bend across San Francisco Bay.
A storm has blown through, leaving the air crystal clear and the bay as flat as glass. It is time for me to unplug my Macbook Pro and iPhone 13 Pro, pick up my various adapters, and pack up.
We arrive in Emeryville 45 minutes early. With any luck, I can squeeze in a ten-mile night hike up Grizzly Peak and still get home in time to watch the ball drop in New York’s Times Square on TV.
I reach the ridge just in time to catch a spectacular pastel sunset over the Pacific Ocean. The omens are there. It is going to be another good year.
I’ll shoot you a Trade Alert whenever I see a window open at a sweet spot on any of the dozens of trades described above.
Good luck and good trading in 2022!
John Thomas
The Mad Hedge Fund Trader
The Omens Are Good for 2022!
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The outlier out there is inexorably linked with technology because, since early 2020, we have experienced a renaissance in efficiency and productivity, largely driven by our weaponization of technology that strongly feeds into the overall economy.
This drove the United States economy to higher growth rates in 2021, and the market isn’t expecting close to 6% of US economic growth in 2022 after the Build Back Better bill was thrown in the dustbin by the Senate.
The truth is that America has never been better at creating quality growth, and that largely flies in the face of mercantilist economies who build inefficient ghost cities or spew out pollution to register growth.
There has never been a better time to be employed in the United States, and the pandemic brought on a revelation of newly formed companies offering highly specialized services in droves.
If you travel abroad, many countries have in fact lost services in aggregate and have largely not replaced because many emerging cities don’t have the spirit of entrepreneurship, access to robust digital infrastructure, or access to cheap capital like in the US.
Although working remotely is not entirely unique to the United States, the U.S. has integrated this phenomenon into the social fabric of daily work life better than almost any other country.
Japanese workers are still required for in-person office time to use the office fax machine and Europe has made inroads to working remotely but workers often don’t push back on their bosses because of the nominal lack of jobs on the European continent.
Here is a list and explanation of the new type of economy we are thriving in in 2022 and the present synergies that could lead the US economy to surprise to the upside for the foreseeable future.
Increased Efficiency and Productivity
Technology has always been a catalyst for efficiency.
Adopting modern technology like the cloud, mobile devices, big data, and analytics help businesses achieve higher levels of efficiency and productivity.
Supplementing these platforms is the ability to sprinkle in AI to supercharge the performance by harnessing data to make predictive decisions in real-time.
Optimal Resource Management
Firms need to maximize their resources for optimal growth, from capital and labor to suppliers and inventory.
Cloud computing has been adopted widely to support resource sharing across different departments within organizations from an IT standpoint.
The internet of things (IoT) is helping businesses track their resources in near real-time, offering greater visibility into how they are being used and where improvement is needed.
Added Resiliency and Agility
Technology is an enabler for business agility. Companies can leverage new technologies like IoT and blockchain to develop highly resilient business ecosystems.
Enhanced Digital Presence
Every company is turning into a digital company if they like it or not. This means having a well-designed website and being easy to navigate, active on social media platforms, and engaging with customers online. The end game here is being able to bypass retail and communicate directly with customers.
Improved Customer Engagements
To overperform, businesses need to engage with their customers meaningfully.
Technology can help businesses do this by providing tools to understand their customer’s needs and wants. Data analytics and AI, for example, can be used to create customer profiles, which can then be used to provide personalized customer experiences.
Increased Responsiveness To Business Needs
Top companies today deploy IT systems with built-in flexibility and scalability, which deliver instantaneous service when need be.
These AI-based technologies can perform repeatable tasks, freeing employees to focus on more valuable work requiring human intelligence. Also, robotic chatbots can assist human employees in providing high-quality customer service.
Cutting Edge Innovation
Today’s employees are technologically savvy, and they expect to use technology in their work.
New technologies like IoT and AI can help harness hidden knowledge within data and transform it into actionable business insights. Such insight-driven companies can make smarter decisions and identify new revenue streams.
Shorter Time To Deliver A Product
Today’s market is full of innovative startups who are able to harness technology so well that they can deliver new products in days if not hours. Businesses need to be able to sense emerging threats and opportunities early on, and being able to bring products to market faster than the competition is crucial to staying ahead.
Increased Revenue Opportunity
Businesses can use big data analytics to identify new market opportunities and potential customer segments. They can also use data-driven marketing techniques like predictive analytics to create targeted marketing campaigns.
Increased Transparency and Visibility
To make informed and timely decisions, businesses need accurate and up-to-date information.
Digital technologies can offer a better understanding of the current realities of the industry and how that translates onto a balance sheet. This allows for better decision-making, more effective business processes, and a more robust overall company culture.
In a Yahoo Finance interview with hedge fund manager Jeffrey Gundlach, Gundlach espouses that he has benefited big by betting the ranch on the American economy up until now, and he pauses to say that emerging economies’ equities are cheap, and he likes to buy assets that are cheap.
But he fails to realize that these economies are cheap for a reason, and even if the quality of life has improved drastically in places like Central Europe and Southeast Asia in the past 30 years, it does not mean the foundations are there for a catch-up trade, let alone a tech catch up trade, that relies on momentum investing.
In fact, America has extended its lead as the place everyone wants to invest in, which is why sovereign wealth funds of all sorts have been looking to get into American single-family homes since the pandemic started.
I believe there is a nice surprise to the upside when it comes to tech stocks because companies are using the 10 different ways listed above to supercharge their business models.
Of course, this also depends on the Fed pulling back from its aggressiveness which isn’t guaranteed.
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“I want to put a ding in the universe.” – Said Co-Founder of Apple Steve Jobs
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Small-cap names tend to have a terrible reputation. However, the possibility of discovering a diamond in the rough pulls traders back in the game over and over.
Fortunately, applying a bit of critical thinking in sifting through the seemingly endless lists of small-cap companies can yield a handful of names worth consideration.
In the biotechnology and healthcare sector, one name that holds the potential is BioDelivery Sciences International (BDSI).
While it’s understandable if you’ve never even heard of BDSI, this company has actually been making waves in the field of severe pain management.
To date, it has three drugs out in the market and holds the patent for a slow-release biofilm technology used to administer these medications. Simply, BDSI is proving to be a profitable and fast-growing company.
The company’s main product is Belbuca, an opioid medication targeting chronic severe pain.
The competitive edge of Belbuca against other drugs is that it’s not an oral pill. Instead, it’s a tiny film that patients keep in their cheeks. This film then slowly dissolves, offering more potent pain relief over time.
Moreover, Belbuca is more difficult to abuse, making it a more attractive option for physicians to prescribe.
At the moment, Belbuca has a 4.7% market share of the long-acting opioid treatment segment.
While that sounds like an unimpressive number, this achievement becomes more pronounced when you find out that Belbuca only held 0.5% of the market when it launched in the fourth quarter of 2017.
By the first quarter of 2021, its market share expanded by 25% year over year, indicating that segment penetration is moving forward swimmingly despite the pandemic.
In fact, Belbuca’s revenues increased by over 95% in the last 3 years.
It also reported that its trailing-12-month earnings since the first quarter of 2020 have skyrocketed to a jaw-dropping 233%.
Recently, it managed to ward off attempts from more prominent names like Teva Pharmaceuticals (TEVA), which hoped to gain access to BDSI’s slow-release biofilm technology.
Bolstering its hold on the pain management market, BDSI has also been successful in marketing Symproic.
This prescription medication, which targets opioid-induced constipation therapies, has seen a steady rise in market share over the past 2 years.
By the first quarter of 2021, Symproic has managed to take hold of 12.6% market share, making it a promising partner to the company’s major growth driver, Belbuca.
Highly aware of the growing competition in the opioid market, BDSI has decided to venture into other segments as well.
In September 2021, the company acquired the rights to acute migraine pain medication Elyxyb for $15 million.
Elyxyb is the first-ever FDA-approved, ready-to-use oral drug aimed to treat acute migraine. In terms of peak sales, BDSI is projected to rake in $350 million to $400 million from this acquisition.
BDSI plans to launch its own take on Elyxyb by the first quarter of 2022, with the goal of adding another catalyst in its growth story and a new revenue stream.
Looking at its history and trajectory, it’s evident that things are heading towards a bright future with BDSI.
This small-cap company managed to sustain the expansion of its market share and boost its sales growth despite the pandemic and the patent challenges from bigger rivals.
Moreover, its balance sheet looks solid. Its margins and cash flow have been exhibiting notable improvements as well.
Simply, there remains no identifiable business concern that might cause it to tumble in the future.
Overall, BDSI’s long-term risk-reward outlook still appears to be attractive regardless of the market’s less-than-stellar reaction to the stock in 2021.
Needless to say, BDSI’s remarkable performance hasn’t been convincing enough for investors to believe that the stock is worth their money.
That turns this promising $315.16 million market cap biotechnology company into an exciting opportunity for deep-value investors searching for diamonds in the rough and an astoundingly cheap growth play.
https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png00Mad Hedge Fund Traderhttps://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.pngMad Hedge Fund Trader2022-01-04 17:00:132022-01-10 00:33:04A Biotech Diamond in the Rough
After Bitcoin’s asymmetric rise to $65,000, the pullback to $45,000 has been hard on all of us.
The momentum sucked out of the asset shows how fortunes can turn on a dime, but that doesn’t mean the price of Bitcoin is dead, it’s just resting.
Without pussyfooting around, the truth is that Bitcoin is highly volatile which is why I do not encourage readers to bet the ranch on it at any moment in time or on any sort of cryptocurrency.
Even the use case of it is constantly attacked almost similar to when Tesla wasn’t Tesla yet and many emerging asset classes but go through teething pains before they mature.
The bottom line is that as volatility increases, the potential to make more money quickly also increases.
Conversely, the bad news is that higher volatility also means higher risk.
When elevated volatility consumes asset prices, the possibility for above-average profit is squarely on the table, but you also run the risk of losing a larger amount of capital in a relatively shorter period of time.
That being said, it’s salient to take measure of what’s going on beneath the surface in order to take a barometer of the health of the industry development.
We aren’t in the business of buying apartment buildings with tofu-like foundations.
This disciplined approach will help you successfully navigate higher volatility asset classes and manage volatility for your benefit—while minimizing risks.
Beneath the surface, the quantity of Bitcoin (BTC) held by private corporations increased significantly during 2021, improving on the 2020 signaling a maturing of the asset class.
Many fortune 500 companies and a smattering of other public companies have scooped up significant Bitcoin purchases and are highly exposed to Bitcoin on public equity markets.
They mainly do this by buying newly minted crypto ETF’s which there are an ever-growing number of choices even though some have chosen to buy directly from crypto brokers.
This isn’t the Bitcoin of 2 years ago, things have moved on quite drastically.
And I am not just talking about MicroStrategy (MSTR) who have been outspoken about their commitment to the digital gold.
MSTR has also been a huge supporter of online seminars aimed to explain the legal considerations for firms seeking to integrate Bitcoin into their businesses and reserves.
As you see, not all companies use Bitcoin the same way, and public corporations are increasingly viewing crypto as contained to only one part of their balance sheet.
For some, they have made it their entire balance sheet on the backs of corporate bond issuances.
This is of course never happened 2 years ago.
CEO of MSTR Michael Saylor’s is a leading business intelligence firm and is known for being particularly bullish on Bitcoin, owning almost $6 billion in crypto assets.
MSTR just bought another 1,914 Bitcoin worth $94 million. The company has gained more than $2.1 billion in profit since its initial Bitcoin purchase in August 2020.
The data shows that digital currency asset management company Grayscale, a de facto bitcoin ETF and proxy of Bitcoin, had gained the highest market share by a landslide at 645,199 Bitcoin by the end of 2021. This took up 71% of the wider market as holdings of all spot ETFs and corporations together totaled 903,988 Bitcoin according to the chart.
MicroStrategy is the largest corporate investor, holding 124,391 Bitcoin valued at around $5.8 billion, according to Bitcoin Treasuries. Second-placed Tesla holds around 43,200 Bitcoin worth roughly $2 billion at current prices.
In 2020, the amount of Bitcoin held by public companies surged 400% in 12 months to $3.6 billion and 2021 showed more inroads while 2022 is poised again to shatter records.
Internally, Bitcoin and cryptocurrencies as a whole are making the right moves to consolidate this asset class as a legitimate industry whether it be DeFi apps or the growing adoption rate.
I see more public companies participating in Bitcoin as a resounding vote of confidence for the currency and this will put the asset in good stead for the long term.
For the short term, the signaling of higher interest rates has really put the kibosh on the price of Bitcoin, but that should be priced into the equation at this point.
The Fed then moving not as fast to raise could offer crypto that narrow path to higher prices.
At the very minimum, the Fed has stolen crypto’s thunder and all attention has gravitated towards what they will do next, and we can see that in how Bitcoin prices have fluctuated because of that.
I expect a slow grind up from the mid-$40,000 if the Fed signals to investors that they will raise rates slower than first imagined.
https://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.png00Mad Hedge Fund Traderhttps://madhedgefundtrader.com/wp-content/uploads/2019/05/cropped-mad-hedge-logo-transparent-192x192_f9578834168ba24df3eb53916a12c882.pngMad Hedge Fund Trader2022-01-04 13:02:522022-01-04 14:20:09Bitcoin Holds Steady
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